Dissecting the gray zone between follicular lymphoma and marginal zone lymphoma using morphological and genetic features
نویسندگان
چکیده
منابع مشابه
Dissecting the gray zone between follicular lymphoma and marginal zone lymphoma using morphological and genetic features.
Nodal marginal zone lymphoma is a poorly defined entity in the World Health Organization classification, based largely on criteria of exclusion and the diagnosis often remains subjective. Follicular lymphoma lacking t(14;18) has similar characteristics which results in a major potential diagnostic overlap which this study aims to dissect. Four subgroups of lymphoma samples (n=56) were analyzed ...
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Composite CD10-positive low-grade B-cell and CD5-positive low-grade B-cell lymphoma is extremely rare. We report a case of a composite follicular lymphoma (FL) and CD5-positive nodal marginal zone lymphoma (NMZL) in a resected inguinal lymph node of a 72-year-old Japanese male. Histologically, multiple follicles had reactive-germinal centers with tingible body macrophages, a thin mantle zone an...
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We present seven cases of mantle cell lymphoma with morphological features of marginal-zone lymphoma. Of particular interest, four of the patients had predominant involvement of the gastrointestinal tract. All cases displayed the translocation t(11;14)(q13;q32) and expressed cyclin D1. Cytogenetic analysis revealed trisomy 3 in one case and somatic hypermutation of immunoglobulin heavy genes co...
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Introduction The current classification of lymphoid neoplasms is based on the integrated utilization of morphological, immunohistochemical, genetic and clinical criteria to define disease entities, which putatively have their origin in a “normal counterpart” in the immune system. The application of modern immunophenotypic and molecular genetic techniques in routine diagnosis has made it possibl...
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ژورنال
عنوان ژورنال: Haematologica
سال: 2013
ISSN: 0390-6078,1592-8721
DOI: 10.3324/haematol.2013.085118